Dating after ovarian cancer
Women diagnosed with ovarian cancer should be offered genetic screening for the relevant gene mutations.58% of patients present with advanced (Stage III or IV) disease If epithelial ovarian cancer is suspected on the basis of physical examination and imaging, an exploratory laparotomy is usually done for histological confirmation, staging and tumour debulking.The standard comprehensive surgical staging approach consists of a total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH and BSO) along with examination of all peritoneal surfaces, an infracolic omentectomy, biopsies of pelvic and para-aortic lymph nodes and clinically uninvolved areas and peritoneal washings.Nearly 70 percent of women who receive an ovarian cancer diagnosis will have a recurrence.Very often these recurrences can be treated with chemotherapy to stop the progression of the disease and improve the woman's survival rate.The highest survival rates are in women under the age of 40 years.Survival rates drop as stage of diagnosis advances, and also range with subtype.Response to chemotherapy is usually good; however, relapse is common and occurs in around 75%. Much of the evidence relates to the most common subtype of epithelial cancer, serous carcinoma; however, it is increasingly clear that the different types need different treatment strategies based on the differing molecular biology involved.Available guidelines apply mainly to epithelial cancers.
Pain in the pelvic area or belly that feels very different from normal indigestion and menstrual problems (i.e., cramps) is indicative of ovarian cancer.
Further management is then determined by the stage and histology of the tumour.